This is the final conference of the COST Action MP1210 The String Theory Universe. It will also continue the long-standing tradition of the annual European Workshop in String Theory and related topics, coinciding with the "XXII European Workshop on String Theory''. The scientific content will reflect the research activities of EU groups participating in the Action, which have been organized in Working Groups. Main subjects will cover gauge/gravity correspondence (fundaments and applications), string phenomenology and black holes, quantum gravity and quantum information. The Conference will provide an overview on the main recent developments in these subjects together with the main results, achievements and innovative mathematical tools that have been developed in the four-year duration of the Action.